This is a provoking breath-taking mysterious thriller about two Chinese chess masters who have been entangled in several serial murder cases in relation to the effect of organ transplants. John Ma (Nicholas Tse) a Hong Kong brave cop, and Calvin Che (Sean Lau) a local criminal psychologist brought together are under the great threat and struggle to define all means evolved from the killings. Their final confrontation will not only uncover the lead behind the scene but also put numerous innocent people in great danger than it is ever known before.